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Table 1 Clinical outcomes of PGT for reciprocal translocation

From: Analysis of meiotic segregation modes in biopsied blastocysts from preimplantation genetic testing cycles of reciprocal translocations

Parameter Population
Patients 89
Cycles 102
Female age (years) 28.8±3.5
Male age (years) 30.2±4.7
Retrieved oocytes 1514
Injected oocytes 1175 (77.6%)
2-Pronuclei zygotes 998 (84.9%)
Embryos used for blastocyst culture 931
Biopsied blastocysts 378 (40.6%)
Diagnosed blastocysts 378 (100%)
Normal/balanced blastocysts 122 (32.3%)
Translocation chromosomes abnormal embryos 209 (55.3%)
Non-translocation chromosomes abnormal embryos 47 (12.4%)
Blastocyst transfer cycles 44
Positive hCG 32 (72.7%)
Biochemical pregnancies 1 (2.3%)
Clinical pregnancies 31 (70.5%)
Spontaneous abortions 2 (4.5%)
Deliveries 29 (65.9%)
  1. Values are n, n (%) or mean±SD
  2. PGT preimplantation genetic testing
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Molecular Cytogenetics

ISSN: 1755-8166